NEET Biology Principle Of Inheritance And Variation Question Bank Assertion and Reason

  • question_answer
    Assertion : Initiation step of protein synthesis in prokaryotes and eukaryotes has several differences. Reason : They both form mRNA - tRNA complex with smaller subunit of ribosome.

    A) If both the assertion and the reason are true and the reason is a correct explanation of the assertion

    B) If both the assertion and reason are true but the reason is not a correct explanation of the assertion 

    C) If the assertion is true but the reason is false

    D) If both the assertion and reason are false

    E) If the assertion is false but reason is true

    Correct Answer: B

    Solution :

    The differences between initiation step of protein synthesis in eukaryotes and prokaryotes are : (i) In prokaryotes initiation factors are three - IF1, IF2 and IF3. Eukaryotes have at least ten initiation factors - eIF1, eIF2, elF3, eIF4A, eIF4B, elF4C, eIF4D, eIF4F, eIF5 and eIF6. (ii) In eukaryotes, formylation of methionine does not take place. In prokaryotes tRNA is charged with formylated methionine. (iii) The larger subunit of ribosome combines with \[40S\text{ }-mRNA\text{ }-tRN{{A}^{Met}}\](in case of prokaryotes, 30S) complex to form intact ribosome. It requires initiation factor IF1 in prokaryotes and factors eIF1, eIF4 (A, B, C) in eukaryotes.


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