JEE Main & Advanced Chemistry Coordination Chemistry Question Bank Critical Thinking Coordination

  • question_answer
    Which of the following is considered as an anticancer species. [CBSE PMT 2004]

    A)

    B)

    C)

    D)

    Correct Answer: A

    Solution :

    Cis Isomer of \[[Pt{{(N{{H}_{3}})}_{2}}C{{l}_{2}}]\] is used as an anticancer drugs for treating several type of malignant tumours. When it is injected into the blood stream the more reactive \[Cl\] groups are lost so the \[Pt\] atom bonds to a \[N\] atom in guanosine (a part of DNA) This molecule can bond to two different guanosine units & by bridging between them it upsets the normal reproduction of DNA.


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