AMU Medical AMU Solved Paper-1998

  • question_answer
    Conversion of phosphoglyceraldehyde to 1, 3- biphosphogly eerie acid is a

    A)  priming reaction only

    B)  redox reaction only

    C)  priming and redox reaction only

    D)  substrate level phosphorylation reaction.

    Correct Answer: D

    Solution :

    : During the glycolytic pathway (dehydrogenation and phosphorylation), in the presence of enzyme glyceraldehyde phosphate dehydrogenase, glyceraldehyde 3-phosphate loses hydrogen to NAD to from\[NAD{{H}_{2}}\]and accepts inorganic phosphate to form\[1:3\] diphosphoglycerate. Glyceraldehyde 3 - phosphate\[+{{H}_{3}}P{{O}_{4}}+NA{{D}^{+}}\] \[1:3\]phosphoglycerate           \[+NADH+{{H}^{+}}\] One of the two phosphates of diphos-phoglycerate is linked by high energy bond. It can synthesis ATP and form 3-phosphoglycerate by using the enzyme phosphoglycerate kinase. The direct synthesis of ATP from metabolites is called substrate level phosphorylation. \[1:3\]diphosphoglycerat\[+ADP\]     3 - phosphoglycerate + ATP.


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