CMC Medical CMC-Medical VELLORE Solved Paper-2015

  • question_answer
    Which of the given statement(s) is/are incorrect?
    I. Downs syndrome is a genetic disorder resulting from bisomy of chromosome 21.
    II. Klinefelters syndrome is an abnormality in man who are always sterile because of an extra X-chromosome.
    III. Huntingtons disease is a sex-linked disorder more common in man because they have a single X-chromosome on which the give is born.
    IV. Women generally do not suffer from haemophilia because its gene is borne on Y-chromosome.

    A)  Only I                  

    B)  II and IV

    C)  II and III              

    D)  Only IV

    E)  Only II

    Correct Answer: B

    Solution :

                    Statement III and IV are Incorrect. Woman generally do not suffer from haemophilia because it is X-linked recessive disorder\[({{X}^{n}}{{X}^{n}}).\] The genotype is rarely found in females in which both the alleles are haemophilic. Huntingtons disease is autosomal dominant disorder and not sex-linked.


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