JCECE Medical JCECE Medical Solved Paper-2002

  • question_answer
    Enzymes that catalyse endergonic synthesis, coupled with exergonic hydrolysis of ATP are:

    A)  ligases          

    B)  isomerase

    C)  lyases          

    D)  transferases

    Correct Answer: A

    Solution :

     Enzymes are proteinaceous compounds that accelerate a chemical reaction without changing its direction. On the basis of types of reaction they catalyse the enzymes are of following six types: Oxidoreductas (i): Transfer of H and O atoms or electrons from one substance to another, e.g., Dehydrogenase, oxidase, catalases. (ii) Transferases: Transfer of a functional group   from   one   substance   e.g., Phosphorylase, kinase. (iii) Hydrolases: Hydrolysis of the substrate e.g., Lipase, amylase, peptidase, protease etc.        (iv) Lyases: Splitting of C-C, C-O, C-N, C-H and other similar bonds not by hydrolysis thereby leaving a double bond. e.g., Decarboxylase, fumarase, aldolase. (v) Isomerases: Change of a substrate into a related  form by intramolecular rearrangement                    e.g., Phosphohexoisomerase. (vi)Ligases (synthatases): Joining of two molecules by forming new bonds with simultaneous break down of ATP e.g., Acyl Co-A synthase, pyruvate carboxylase.


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