JCECE Medical JCECE Medical Solved Paper-2009

  • question_answer
    Sertoli cells are regulated by the pituitary hormone known as

    A)  FSH              

    B)  GH

    C)  prolactin        

    D)  LH

    Correct Answer: A

    Solution :

     Sertoli cells are the cells that line the seminiferous tubules in the testis. These cells protect the spermatids and convey nutrients to both the developing and mature Spermatozoa. Sertoli cells are regulated by-FSH (Follicle Stimulating Hormone) as the FSH receptors are confined to the sertoli cells. FSH stimulates sertoli cells to produce androgen-binding protein and inhibin; and together with testosterone, promotes the proliferation of Sertoli cells. Growth Hormone (GH) or Somatotropin (STH) is secreted from adenohypophysis of pituitary gland. It stimulates cellular growth and proliferation, growth and repair of bones, muscles and connective tissue. In the liver cells it promotes, glycogenesis, deamination and glycogenesis. Prolactin (PRL), Lactogenic, Luteotropic (LTH) or Mammotropic Hormone (MTH) is secreted by the lactotroph cells of anterior pituitary. In humans, it may act as a mild growth hormone, but its main physiological effect is to activate growth of breasts during pregnancy and secretion of milk by mammary glands after child birth. Luteinizing Hormone (LH) or Interstitial Cells to stimulating hormone (ICSH) is secreted from adenohypophysis of pituitary gland. In man, it stimulates the growth and function of the interstitial cells of testes (Leydig cells), which secrete the male hormone (androgens) to regulate the development of secondary sexual characters. In women, it stimulates the last stages of oogenesis, ovulation, development of corpus luteum and secretion of progesterone  by the corpus luteum.


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