Punjab Medical Punjab - MET Solved Paper-2005

  • question_answer
    Which of the following is a typical example of feed back inhibition?

    A)  Sulpha drugs and folic acid synthesizer bacteria

    B)  Allosteric inhibition of hexokinase by glucose \[6-\]phosphate

    C)  Reaction between succinic dehydrogenase and succinic acid

    D)  Cyanide and cytochrome reaction

    Correct Answer: B

    Solution :

    In allosteric inhibition or feedback inhibition accumulation of the final product of the reaction is capable of inhibiting the first step of reaction. Example: Aspartate\[\xrightarrow{{}}\]\[Aspartyl\text{ }\underset{\downarrow }{\mathop{phosphate}}\,\]\[\xrightarrow{{}}\]Aspartyl semialdehyde Lysine. feedback inhibition


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