Punjab Medical Punjab - MET Solved Paper-2006

  • question_answer
    If one strand of DNA has the sequence \[ATCGTATG\], the sequence in the complementary strand would be:

    A) \[TAGCTTAC\]                  

    B) \[TCACATAC\]

    C) \[TAGCATAC\]                 

    D) \[TACGATAC\]

    Correct Answer: C

    Solution :

    Because of size and geometries of the bases, the only possible pairings in DNA are between \[G\] (guanine) and \[C\] (cytosine) through three H-bonds and between \[A\] (adenine) and \[T\] (thymine) through two H-bonds. Hence, \[\underset{\begin{smallmatrix}  | \\  T \end{smallmatrix}}{\mathop{A}}\,\underset{\begin{smallmatrix}  | \\  A \end{smallmatrix}}{\mathop{T}}\,\underset{\begin{smallmatrix}  | \\  G \end{smallmatrix}}{\mathop{C}}\,\underset{\begin{smallmatrix}  | \\  C \end{smallmatrix}}{\mathop{G}}\,\underset{\begin{smallmatrix}  | \\  A \end{smallmatrix}}{\mathop{T}}\,\underset{\begin{smallmatrix}  | \\  T \end{smallmatrix}}{\mathop{A}}\,\underset{\begin{smallmatrix}  | \\  A \end{smallmatrix}}{\mathop{T}}\,\underset{\begin{smallmatrix}  | \\  C \end{smallmatrix}}{\mathop{G}}\,\]


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