question_answer 40)

  A person with sickle-cell anaemia is (a) more prone to malaria                                            (b) more prone to typhoid (c) less prone to malaria                                (d) less prone to typhoid

Answer:

                    (c) Sickle-cell anaemia is related to malaria not to typhoid and person suffering from sickle-cell anaemia are resistant to malarial parasite ar RBC of sickle-cell anaemic patients is distored in shape that not affected by Plasmodium sp.It is known that heterozygotes (), having both types of haemoglobinshow resistance to malarial infection because the body targets the P.falciparum infected cells for destruction. In contrast, individuals homozygous for normal haemoglobin () suffer high mortality rates in early childhood due to malarial infection.