12th Class Biology Molecular basis of inheritance

  • question_answer 68)   The total number of genes in humans is far less (<25000) than the previous estimate (up to 140000 gene). Comment.


                      The total number of genes is estimated at 25000 much lower than previous estimates of140000 that had been based on extrapolations from gene-rich areas as opposed to a composite of gene-rich and gene-poor areas.Almost all (99.9%) nucleotide bases are exactly the same in all people. Functions for over50% discovered genes are not known yet. Scientist have identified about 1.4 million locations where single-base DNA difference (SNPs or Single Nucleotide Polymorphisms)occur in humans. This information promises to revolutionize the processes of finding chromosomal locations for disease-associated sequence and tracing human history.

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