12th Class Biology Molecular basis of Inheritance / विरासत का आणविक आधार Question Bank

done SAT (MCQs) - Molecular Basis of Inheritance Total Questions - 35

• question_answer1)
  Which of the following rRNAs acts as structural RNA as well as ribozyme in bacteria?
  A)
  23 S rRNA done clear
  B)
  5.8 S rRNA done clear
  C)
  5 S rRNA done clear
  D)
  18 S rRNA done clear
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• question_answer2)
  A molecule that can act as a genetic material must fulfill the traits given below, except
  A)
  It should be unstable structurally and chemically done clear
  B)
  It should provide the scope for slow changes that are required for evolution done clear
  C)
  It should be able to express itself in the form of 'Mendelian characters' done clear
  D)
  It should be able to generate its replica done clear
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• question_answer3)
  DNA-dependent RNA polymerase catalyzes transcription on one strand of the DNA which is called the
  A)
  Alpha strand done clear
  B)
  Antistrand done clear
  C)
  Template strand done clear
  D)
  Coding strand done clear
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• question_answer4)
  In a 3.2 kbp long piece of DNA, 820 adenine bases were found. What would be the number of cytosine bases?
  A)
  780 done clear
  B)
  1560 done clear
  C)
  740 done clear
  D)
  1480 done clear
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• question_answer5)

  Some of the steps of DNA finger printing are given below. Identify the correct sequence

  [a] Electrophoresis of DNA fragments

  [b] Hybridisation with DNA probe

  [c] Digestion of DNA by restriction endo- nucleases

  [d] Autoradiography

  [e] Blotting of DNA fragments to nitrocellulose membrane

  A)
  c-a-b-e-d done clear
  B)
  c-a-e-b-d done clear
  C)
  a-e-c-b-d done clear
  D)
  a-c-e-d-b. done clear
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• question_answer6)
  If the sequence of bases in the coding strand of a double stranded DNA is 5-GTTCGAGTC-3-, the sequence of bases in its transcript will be
  A)
  5-GACUCGAAC-3- done clear
  B)
  5-CAAGCUCAG-3- done clear
  C)
  5-GUUCGAGUC-3- done clear
  D)
  5-CUGAGCUUG-3- done clear
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• question_answer7)
  The final proof for DNA as the genetic material came from the experiments of
  A)
  Hargobind Khorana done clear
  B)
  Griffith done clear
  C)
  Hershey and Chase done clear
  D)
  Avery, Mcleod and McCarty done clear
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• question_answer8)
  The association of histone Hi with a nucleosome indicates
  A)
  The DNA double helix is exposed done clear
  B)
  Transcription is occurring done clear
  C)
  DNA replication is occurring done clear
  D)
  The DNA is condensed into a Chromatin Fibre done clear
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• question_answer9)
  DNA fragments are
  A)
  Either positively or negatively charged depending on their size done clear
  B)
  Positively charged done clear
  C)
  Negatively charged done clear
  D)
  Neutral done clear
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• question_answer10)
  Which of the following RNAs should be most abundant in animal cell?
  A)
  mi-RNA done clear
  B)
  r-RNA done clear
  C)
  t-RNA done clear
  D)
  m-RNA done clear
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• question_answer11)
  During DNA replication, Okazaki fragments are used to elongate
  A)
  The lagging strand away from the replication fork. done clear
  B)
  The leading strand towards replication fork. done clear
  C)
  The lagging strand towards replication fork. done clear
  D)
  The leading strand away from replication fork. done clear
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• question_answer12)
  If there are 999 bases in an RNA that codes for a protein with 333 amino acids and the base at position 901 is deleted such that the length of the RNA becomes 998 bases, how many codons will be altered?
  A)
  333 done clear
  B)
  1 done clear
  C)
  11 done clear
  D)
  33 done clear
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• question_answer13)
  Spliceosomes are not found in cells of
  A)
  Bacteria done clear
  B)
  Plants done clear
  C)
  Fungi done clear
  D)
  Animals done clear
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• question_answer14)

  What is correct about the labelling a, b and c

  A)
  a-histone octamer, c-DNA done clear
  B)
  b-Hl histone, c-histone octamer done clear
  C)
  a-Hl histone, b-DNA done clear
  D)
  a-histone octamer, c-Hl histone. done clear
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• question_answer15)
  Match the columns and find the correct options

  	I		II
  [a]	GGG	(i)	Proline
  [b]	UUU	(ii)	Glycine
  [c]	CCC	(iii)	Arginine
  [d]	AAA	(iv)	Phenylalanine

  A)
  a-v, b-ii, c-i, d-ii done clear
  B)
  a-iv, b-iii, c-i, d-ii done clear
  C)
  a-ii, b-iv, a-i, d-v done clear
  D)
  a-i, b-ii, c-iii, d-iv done clear
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• question_answer16)
  Select the correct match from the following combinations.
  A)
  \[{{F}_{2}}\times \]Recessive parent - Dihybrid cross done clear
  B)
  T.H. Morgan - Transduction done clear
  C)
  Ribozyme - Nucleic acid done clear
  D)
  G. Mendel - Transformation done clear
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• question_answer17)
  The experimental proof for semiconservative replication of DNA was first shown in a
  A)
  Bacterium done clear
  B)
  Plant done clear
  C)
  Fungus done clear
  D)
  Virus done clear
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• question_answer18)
  Select the correct match from the following combinations.
  A)
  Alfred Hershey and Martha Chase - TMV done clear
  B)
  Matthew Meselson and F. Stahl - Pisumsativum done clear
  C)
  Alee Jeffreys - Streptococcus pneumonia done clear
  D)
  Francois Jacob and Jacques Monod - Lac operon done clear
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• question_answer19)
  Many ribosomes may associate with a single mRNA to form multiple copies of a polypeptide simultaneously. Such strings of ribosomes are termed as
  A)
  Polyhedral bodies done clear
  B)
  Plastidome done clear
  C)
  Poly some done clear
  D)
  Nucleosome done clear
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• question_answer20)
  All of the following are part of an operon except
  A)
  structural genes done clear
  B)
  an enhancer done clear
  C)
  an operator done clear
  D)
  an promoter done clear
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• question_answer21)
  AGGTATCGCAT is a sequence from the coding strand of a gene. What will be the corresponding sequence of the transcribed mRNA?
  A)
  UGGTUTCGCAT done clear
  B)
  ACCUAUGCGAU done clear
  C)
  AGGUAUCGCAU done clear
  D)
  UCCAUAGCGUA done clear
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• question_answer22)
  Match column-I to the column-II and select the option having correct matching

  	Column - I		Column - II
  [a]	Bacteriophage\[\lambda \]	(i)	5386 nucleotide
  [b]	E.coli	(ii)	\[3.3\times {{10}^{9}}bp\]
  [c]	Human genome	(iii)	\[4.6\times {{10}^{6}}\,bp\]
  [d]	\[\phi \times 174\]	(iv)	48502 bp

  A)
  A - (iv), B - (iii), C - (ii), D - (i) done clear
  B)
  A - (iii), B - (ii), C - (i), D - (iv) done clear
  C)
  A - (iv), B - (iii), C - (i), D - (ii) done clear
  D)
  A - (iv), B - (i), C - (ii), D - (iii) done clear
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• question_answer23)
  Which of the following correctly assigns the codons for glycine?
  A)
  GGG, GGC, GGA done clear
  B)
  AAA, AAG, AAC done clear
  C)
  AUG, AUA, AUC done clear
  D)
  CCC, CCG, CGA done clear
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• question_answer24)
  Select the wrong pair
  A)
  RNA polymerase I - Sn RNA 5S rRNA, r-RNA done clear
  B)
  RNA polymerase I - r-RNA done clear
  C)
  RNA polymerase II - hnRNA done clear
  D)
  RNA polymerase III - tRNA done clear
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• question_answer25)
  In the diagram given figure of Lac operon
  A)
  i - Represser, z - P-galactosidase, y-Permease, a- Transacetylase done clear
  B)
  i - Inhibitor, z - Represser, y - Transacetylase, a - Permease done clear
  C)
  i - Inducer, z - P-galactosidase, y - Permease, a - Represser done clear
  D)
  i - P-galactosidase, z - Represser, y- Permease, a - Transacetylase done clear
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• question_answer26)

  Directions : (26 - 30)

  In the following questions a statement of assertion followed by a statement of reason is given.

  Choose the correct answer out of the following choices :

  Assertion: Euchromatin is transcriptionally active chromatin.

  Reason: Heterochromatin is transcriptionally inactive chromatin.

  A)
  Assertion and reason both are correct statements and reason is correct explanation for assertion. done clear
  B)
  Assertion and reason both are correct statements but reason is not correct explanation for assertion. done clear
  C)
  Assertion is correct statement but reason is wrong statement. done clear
  D)
  Assertion is wrong statement but reason is correct statement. done clear
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• question_answer27)

  Assertion: S - strain of Streptococcus pneumonlae is virulent in nature.

  Reason: R - strain of Streptococcus pneumoniae is non - virulent in nature.

  A)
  Assertion and reason both are correct statements and reason is correct explanation for assertion. done clear
  B)
  Assertion and reason both are correct statements but reason is not correct explanation for assertion. done clear
  C)
  Assertion is correct statement but reason is wrong statement. done clear
  D)
  Assertion is wrong statement but reason is correct statement. done clear
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• question_answer28)

  Assertion: DNA and RNA are able to generate their replica inside the cell.

  Reason: Protein also show replication power inside the cell.

  A)
  Assertion and reason both are correct statements and reason is correct explanation for assertion. done clear
  B)
  Assertion and reason both are correct statements but reason is not correct explanation for assertion. done clear
  C)
  Assertion is correct statement but reason is wrong statement. done clear
  D)
  Assertion is wrong statement but reason is correct statement. done clear
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• question_answer29)

  Assertion: Leading strand of DNA grows continuously during replication.

  Reason: Lagging strand of DNA grows discontinuously during replication.

  A)
  Assertion and reason both are correct statements and reason is correct explanation for assertion. done clear
  B)
  Assertion and reason both are correct statements but reason is not correct explanation for assertion. done clear
  C)
  Assertion is correct statement but reason is wrong statement. done clear
  D)
  Assertion is wrong statement but reason is correct statement. done clear
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• question_answer30)

  Assertion: Prokaryotes have monocistronic mRNA in nature.

  Reason: Eukaryotes cells also have monocistronic mRNA in nature.

  A)
  Assertion and reason both are correct statements and reason is correct explanation for assertion. done clear
  B)
  Assertion and reason both are correct statements but reason is not correct explanation for assertion. done clear
  C)
  Assertion is correct statement but reason is wrong statement. done clear
  D)
  Assertion is wrong statement but reason is correct statement. done clear
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• question_answer31)

  Directions : (31 - 35)

  Read the passage given below and answer the following questions.

  Regulation of gene expression refers to a very broad term that may occur at various levels. Considering that gene expression results in the formation of a polypeptide, it can be regulated at several levels. In eukaryotes, the regulation could be exerted at

  (i) transcriptional level i.e., formation of primary transcript,

  (ii) processing level i.e., regulation of splicing,

  (iii) transport of mRNA from nucleus to the cytoplasm,

  (iv) translational level.

  The genes in a cell are expressed to perform a particular function(s). For example, if an enzyme called beta-galactosidase is synthesised by E. coli, it is used to catalyse the hydrolysis of a disaccharide, lactose into galactose and glucose; the bacteria use them as a source of energy. Hence, if the bacteria do not have lactose around them to be utilised for energy source, they would no longer require the synthesis of the enzyme beta-galactosidase. Therefore, in simple terms, it is the metabolic, physiological or environmental conditions that regulate the expression of genes. The development and differentiation of embryo into adult organisms are also a result of the coordinated regulation of expression of several sets of genes. In prokaryotes, control of the rate of transcriptional initiation is the predominant site for control of gene expression. In a transcription unit, the activity of RNA polymerase at a given promoter is in turn regulated by interaction with accessory proteins, which affect its ability to recognise start sites. These regulatory proteins can act both positively (activators) and negatively (repressers). The accessibility of promoter regions of prokaryotic DNA is in many cases regulated by the interaction of proteins with sequences termed operators. The operator region is adjacent to the promoter elements in most operons and in most cases the sequences of the operator bind a represser protein. Each operon has its specific operator and specific represser, e.g., lac operator is present only in the lac operon and it interacts specifically with lac represser only.

  Gene expression in the cell results in the formation of
  A)
  Polysaccharide done clear
  B)
  Polypeptide done clear
  C)
  Glucose and fructose done clear
  D)
  Deoxyribose and ribose done clear
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• question_answer32)
  Beta - galactosidase in E. coli is used to catalyse the hydrolysis of
  A)
  Monosaccharide done clear
  B)
  Polysaccharide done clear
  C)
  Disaccharide done clear
  D)
  Trisaccharide done clear
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• question_answer33)
  Nature of a represser in lac operon is
  A)
  Lipid only done clear
  B)
  Polysaccharide only done clear
  C)
  Nucleic acid only done clear
  D)
  Protein only done clear
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• question_answer34)
  Regulatory proteins in the gene expression can act as
  A)
  Activators only done clear
  B)
  Repressers only done clear
  C)
  Both of the above done clear
  D)
  None of the above done clear
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• question_answer35)
  Lac operon is stand for
  A)
  Lactic acid operon done clear
  B)
  Leucine operon done clear
  C)
  Lactose operon done clear
  D)
  Lysine operon done clear
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