question_answer

  There is growing interest in the use of chelate therapy in medicinal chemistry. An example is the treatment of problems caused by the presence of metals in toxic proportions in plant/animal systems. Detection of cations through coloured complex formation is done in qualitative analysis. Read the above passage and answer the following questions. (a) Name the chelating agents that can remove copper, iron and lead from water,                           [1] (b) Name the compound that inhibits the growth of tumours.                                                                    [1] (c) Recent studies show that cis-platin can cause serious side effects; including severe kidney damage. What is the alternative medicine?                                                                                                                                    [1]

Answer:

  (a) Copper, Iron D-penicillamine desferrioxime D Lead EDTA                       [1] (b) O's-platin                                                     [1] (c) Cis-platin is being replaced by tran5-isomer n = 2 to 6 [1]