| Column-I | Column-II | ||
| A. | Autosomal recessive trait | I. | Down?s syndrome |
| B. | Sex-linked recessive trait | II. | Phenylketonuria |
| C. | Metabolic error linked autosomal recessive | III. | Haemophilia |
| D. | Additional 21st chromosome | IV. | Sickle cell anaemia |
A) A - II; B - I; C - IV; D - III
B) A - IV; B - I; C - II; D - III
C) A - IV; B - III; C - II; D - I
D) A - III; B - IV; C - I; D - II
Correct Answer: C
Solution :
Sickle cell anaemia is an autosomal recessive trait. Haemophilia is a sex-linked recessive trait. Metabolic error linked to autosomal recessive is Phenylketonuria. It is an inherited disease due to faulty metabolism of phenylalanine. The affected Individual lacks an enzyme that converts the amino acid phenylalanine into tyrosine. It is characterised by the presence of phenylketones in the urine and usually first noted by signs of mental retardation in infancy. Down's syndrome occurs due to presence of an additional 21st chromosome.
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