A) after entry of sperm but before fertilization
B) after fertilization
C) before entry of sperm into ovum
D) simultaneously with first cleavage
Correct Answer: A
Solution :
Extrusion of second polar body from egg nucleus occurs after entry of sperm but before fertilization. The entry of sperm into the ovum induce completion of the meiotic division of the secondary oocyte. Entry of sperm causes breakdown of metaphase promoting factor (MPF) and turns on anaphase promoting complex (APC).
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