A) \[\alpha \]ketoglutarate
B) malate
C) malonate
D) oxaloacetate
Correct Answer: C
Solution :
Malonate is a powerful inhibitor of cellular respiration because it binds to the active site of the succinate dehydrogenase in the citric acid cycle but does not react, thereby competes \[-C{{H}_{2}}-C{{H}_{2}}-\]group as in succinate which is required for dehydrogenation. For the oxidative phosphorylation reaction, malonate is an inhibitor for complex II which again contain succinate dehydrogenase.
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