A) Variable region of heavy chain
B) Variable region of both heavy and light chain
C) Variable region of light chain
D) Constant region of both light and heavy chain
Correct Answer: B
Solution :
Each antibody consists of 4 polypeptides - two heavy chains & two light chains joined to form a ?Y? shaped molecule. The amino acid sequence in the tips of the ?Y? varies greatly among different antibodies. This variable region, composed of 110 - 130 amino acids, give the antibody its specificity for binding antigen. The variable region includes the ends of the light & heavy chains.
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