NEET AIPMT SOLVED PAPER SCREENING 2005

  • question_answer
                    Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain?

    A)                                                                                                                                                                                            Lipase              

    B)                 Exonuclease      

    C)                 Endonuclease    

    D)                 Protease

    Correct Answer: C

    Solution :

                    DNAase (or deoxyribonuclease) or simply nuclease is an enzyme which breaks down DNA by hydrolysis of the phosphodiester bonds of its sugar-phosphate back bone. Depending on the position of hydrolysing phosphodiester bonds, nucleases are of two types:                 (i) Endonucleases            (ii) Exonucleases.                 Endonucleases hydrolyse internal phosphodiester bonds in a polynucleotide chain (i.e., DNA). While exonucleases hydrolyse terminal phosphodiester bonds in a polynucleotide chain (i.e., DNA).


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