A) this disease is due to an X-linked dominant mutation
B) a greater proportion of girls die in infancy
C) this disease is due to an X-linked recessive mutation
D) this disease is due to a Y-linked recessive mutation
Correct Answer: C
Solution :
Haemophilia, a hereditary (recessive X-linked) disease is caused due to fault in genes which controlling the factor VIII and IX, located on X-chromosome. The male carries only one X-chromosome, his other sex chromosome which carries no genes for blood clotting, so the condition is usually seen only in males where only one faulty chromosome is needed. While a female with one faulty X-chromosome will be carrier. So, in females two faulty X-chromosome are needed to cause the disease.
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