AMU Medical AMU Solved Paper-1997

  • question_answer
    The activity of the enzyme threonine deaminase is inhibited by

    A)  malonic acid

    B)  sulphur drugs

    C)  glucose-6-phosphate

    D)  isoleucine.

    Correct Answer: D

    Solution :

    : The amino acid isoleucine in E. coli is synthesized from threonine. Whenever the level or amount of isoleucine increases beyond the limit of requirement, it stops its own production by inhibiting the activity of the enzyme threonine deaminase, which catalyses the first step of reaction. This type of inhibition is termed as feed-back inhibition.


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