AMU Medical AMU Solved Paper-1997

  • question_answer Interferon\[\beta \]is also termed as

    A)  immune interferon

    B)  fibroblast interferon

    C)  leucocyte interferon

    D)  anti-immune interferon..

    Correct Answer: B

    Solution :

    : Interferon was discovered over 40 years ago by Issacs and Lindemann who showed that supernatant fractions from virus-infected cells contained a protein that could confer resistance to infection to other cells. This substance did not act directly on the virus, rather it acted on the cells to make them resistant to infection. IF N is one of the first lines of defense against viruses because it is induced early after virus infection before any of the other defense mechanisms appear (e.g. antibody, Tc cells etc.) There are three types of interferon, IFN-alpha (also known as leukocyte interferon), IFN-beta (also known as fibroblast interferon) and IFN-gamma (also known as immune interferon). IFN-alpha and IFN-beta are also referred to as Type I interferon and IFN-gamma as Type II.


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