AMU Medical AMU Solved Paper-2014

  • question_answer
    During polynucleotide synthesis by the following enzymes, in which case elongation occurs in \[5\to 3\] direction?

    A)  DNA polymerase

    B)  RNA polymerase

    C)  Reverse transcriptase

    D)  All of the above

    Correct Answer: A

    Solution :

                     The DNA polymerase enzyme catalyses polymerisation only in one direction, i.e., \[5\to 3\], during   polynucleotide   synthesis.   In   a transcription unit, RNA polymerase also catalyses the polymerisation in only one direction, i.e., \[5\to 3\]. Retroviruses are equipped with an enzyme called reverse transcriptase which transcribes an RNA template into DNA.


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