A) Low \[p{{O}_{2}}\], high \[pC{{O}_{2}}\], high \[{{H}^{+}}\]
B) High \[p{{O}_{2}}\], high \[pC{{O}_{2}}\], low \[{{H}^{+}}\]
C) High \[pC{{O}_{2}}\], low \[pC{{O}_{2}}\], low \[{{H}^{+}}\]
D) Low \[p{{O}_{2}}\], low \[pC{{O}_{2}}\], low \[{{H}^{+}}\]
Correct Answer: A
Solution :
Low pH or high \[{{H}^{+}}\] concentration, high \[pC{{O}_{2}}\]concentration and low \[p{{O}_{2}}\] concentration favours \[{{O}_{2}}\] dissociation from haemoglobin in tissues and \[\therefore \] releases \[{{O}_{2}}\] in tissues. Conversely, a high pH, low \[pC{{O}_{2}}\] or low 2, 3 biphosphoglycerate level favours relaxed state of Hb and thereby binding of \[{{O}_{2}}\].
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