BCECE Medical BCECE Medical Solved Papers-2015

  • question_answer
    Addition of a competitive inhibitor to any reaction mixture will

    A)  decrease km       

    B)  decrease \[{{V}_{\max }}\]

    C)  increase km        

    D)  increase \[{{V}_{\max }}\]

    Correct Answer: C

    Solution :

    Competitive inhibitors are substances similar to a substrate for a specific enzyme. It actively competes with the substrate for binding to the active site of an enzyme. As a result, the substrate do not binds and enzymes action declines. In this kind of inhibition, the \[{{V}_{\max }}\]remains contant (unchanged) and km value increases, e.g, malonic acid is competitive inhibitor of succinic acid.


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