CET Karnataka Medical CET - Karnataka Medical Solved Paper-2006

  • question_answer
    Variable number of tandem repeats (VNTRs) in the DNA molecule are highly useful in:

    A)  recombinant DNA technology

    B)  DNA finger printing

    C)  monoclonal antibody production

    D)  stem cell culture

    Correct Answer: B

    Solution :

    Alee Jeffreys et al (1985) developed the technique of genetic analysis and forensic medicine called DNA finger printing. DNA finger print of an individual is prepared by digesting its DNA with a restriction enzyme and the digested DNA is subjected to electrophoresis and southern hybridization with a probe specific for a highly variable region. The chromosome of every human cell contain scattered through their DNA, short highly repeated 15 nucleotide segments called mini satellites or variable number Tandem Repeat (VNTR). Genetic engineering involves transfer or replacement of genes therefore also known as recombinant DNA technology. Monoclonal  antibodies  are  specialized antibodies which are specific to only one type of antigen.


You need to login to perform this action.
You will be redirected in 3 sec spinner