CET Karnataka Medical CET - Karnataka Medical Solved Paper-2007

  • question_answer
    The net gain of ATP during glycolysis is

    A)  six           

    B)  eight

    C)  two          

    D)  four

    Correct Answer: C

    Solution :

    Glycolysis is common pathway in both aerobic and anaerobic respiration and occurs in the cytosol of all living cells of prokaryotes as well as eukaryotes. It is basically an anaerobic pathway as it does not use oxygen. It is an enzyme controlled 10 steps reaction by which glucose, fructose or sucrose is reduced to form pyruvic acid with the production of ATP and \[NAD{{H}_{2}}.\] The net result of glycolysis is- (i) 2-mole of pyruvic acid (ii) 2-mole of \[{{H}_{2}}O\]                        (iii) 2-mole of ATP (iv) 2-mole of \[NAD{{H}_{2}}\] The overall reaction of glycolysis is- Glucose \[+2NAD\underset{_{_{\downarrow }}}{\mathop{+}}\,\underset{Glycolysis}{\mathop{2ADP}}\,+2{{H}_{3}}P{{O}_{4}}\] \[2-pyruvate+2NADH+2{{H}^{+}}+2ATP+2{{H}_{2}}O\]The two molecules of \[NADH+{{H}^{+}}\]enter into mitochondria and oxidized through ETS. Thus, the net gain of ATP during glycolysis is 2ATP.


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