CET Karnataka Medical CET - Karnataka Medical Solved Paper-2008

  • question_answer
    An autosomal genetic disorder called cri-du-chat is caused due to

    A)  non - disjunction

    B)  mutation

    C)  deletion        

    D)  duplication

    Correct Answer: C

    Solution :

    Human babies missing (deletion) a portion of the short arm of chromosome 5 (autosome) have a distinctive cat-like cry hence, the french name Cri du-chat syndrome. They are also mentally retarded have malformation in the larynx, moon faces saddle noses, small mandibles, malformed lowset ears and microcephaly.


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