CET Karnataka Medical CET - Karnataka Medical Solved Paper-2011

  • question_answer
    Which one of the following reactions is an example of oxidative decarboxylation?

    A)  Conversion of succinate to fumerate

    B)  Conversion of fumerate to malate

    C)  Conversion of pyruvate to acetyl Co-A

    D)  Conversion of citrate to isocitrate

    Correct Answer: C

    Solution :

    The pyruvic acid formed during glycolysis enters to mkochondria where oxidative decarboxylation takes place and acetyl Co-A is formed. It occurs in presence of\[NA{{D}^{+}}\], pyruvic acid dehydrogenase complex and coenzyme-A. Pyruvic acid \[\xrightarrow[{}]{{}}\]Acetyl \[Co-A+NDH\]\[+{{H}^{+}}+C{{O}_{2}}+NA{{D}^{+}}\]


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