CET Karnataka Medical CET - Karnataka Medical Solved Paper-2012

  • question_answer
    The site of Krebs cycle is

    A)  cytoplasm

    B)  mitochondrial matrix

    C)  intermembrane space of mitochondria

    D)  rackers particles

    Correct Answer: B

    Solution :

    : Krebs cycle also known as citric acid cycle or tricarboxylic acid cycle is a stepwise oxidative and cyclic degradation of activated acetate derived from pyruvate. The cycle was discovered by Hans Krebs. It is a nearly universal central  catabolic pathway in which compounds derived  from the breakdown of carbohydrates, fats and proteins are oxidized to \[C{{O}_{2}}\], in which most of the energy of oxidation gets temporarily held in the electron carriers \[FAD{{H}_{2}}\]and NADH. It occurs in mitochondrial matrix as enzymes required for Krebs cycle are present in the matrix of mitochondria in close proximity to the electron transport chain. For example, aconitase, iso-citric dehydrogenase, synthetase, fumarase, etc.


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