A) Live R strain \[+\] DNA from S strain \[+\] RNA ase
B) Live R strain \[+\] DNA from S strain \[+\]DNA ase
C) Live R strain \[+\] Denatured DNA of S strain \[+\] protease
D) Heat killed R strain \[+\] DNA from S strain \[+\] DNAase
Correct Answer: B
Solution :
: R-strain is rough and harmless, while S-strain is smooth and virulent form of Streptococcus pneumoniae. in their expenment, Avery et al., found out that only when DNA from S-type bacteria is added to a culture of R-type bacteria, R-type get converted to S-type strain. This transformation of R into S-type did not occur on addition of carbohydrate or protein from S-type bacteria. Moreover, in the first scenario, if D Nase enzyme was added, i.e., Live R strain + DNA from S strain + D Nase, transformation would not have occurred, proving conclusively that DNA, indeed is the genetic material.
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