CET Karnataka Medical CET - Karnataka Medical Solved Paper-2015

  • question_answer
    Identify the wrong statement.

    A)  Alleles b and c also produce sugar.

    B)  Alleles \[{{I}^{A}}\] and \[{{I}^{B}}\] produce sugars.

    C)  When \[{{I}^{B}}\] and b or i are present only \[{{I}^{B}}\] is expressed.

    D)  Both \[{{I}^{A}}\] and \[{{I}^{B}}\] are present together and they express because of co-dominance.

    Correct Answer: A

    Solution :

    : ABO blood group in humans is controlled by three multiple alleles \[{{I}^{A}}\], \[{{I}^{B}}\] and i. There are two types of antigens present in the surface coating of red blood cells - A and B. The  \[{{I}^{A}}\]and \[{{I}^{B}}\] alleles produce enzyme glycosyltransferase for synthesis of sugars. The sugars are attached to lipids and produce glycolipids. These glycolipids then associate with membrane of RBC to form blood group antigens. Allele i does not produce any enzyme/antigen. Both \[{{I}^{A}}\] and \[{{I}^{B}}\] are codominant (i.e., able to express themselves in presence of each other) but are dominant over i.


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