CET Karnataka Medical CET - Karnataka Medical Solved Paper-2015

  • question_answer
    Which vector can clone a small fragment of DNA?

    A)  Plasmid

    B)  Bacterial artificial chromosome

    C)  Cosmid

    D)  Yeast artificial chromosome

    Correct Answer: A

    Solution :

    : The vectors are DNA molecules that can carry foreign DNA segment and replicate inside the host cell. Plasmids are extra-chromosomal, self-replicating, circular, ds DNA molecules. Plasmid vectors are used to carry small DNA fragments usually of\[100-1000\text{ }bp\]. Cosmids are used to clone DNA fragments upto 45Kb in length, bacterial artificial chromosomes (BAC) can accommodate 300-350 Kb of foreign DNA and yeast artificial chromosomes (YAC) can clone DNA fragments of more than 1 Mb in size.


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