J & K CET Medical J & K - CET Medical Solved Paper-2014

  • question_answer
    Who gave semi-conservative mode of DNA replication for the first time in E.coli with the help of 15 N heavy nitrogen isotope?

    A)  Watson and Crick

    B)  Kornberg and Ochoa

    C)  Meselson and Stahl

    D)  Luria and Delbruck

    Correct Answer: B

    Solution :

     Mathew Messelson and Franklin Stahl (1957-58)  gave/prooved  semi-conservative mode of DNA replication for the fist time in bacterium E coy/with help of\[^{15}Na\]heavy isotope of nitrogen as postulated previously by Watson and Crick. Kornberg and Ochoa carried out the first in vitro synthesis of DNA with template and RNA respectively.


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