JCECE Medical JCECE Medical Solved Paper-2006

  • question_answer
    Isocyanide is prepared by:

    A)  Friedel Crafts reaction

    B)  Wurtzs reaction

    C)  Williamson synthesis

    D)  Carbylamine reaction

    Correct Answer: D

    Solution :

     Isocyanides are prepared by carbylamines reaction. In this treated with chloroform, and \[\text{NaOH}\]or KOH to give isocyanide. (unpleasant smelling compound) \[CHC{{l}_{3}}+3KOH+\underset{\begin{smallmatrix}  \text{primary} \\  \text{amine} \end{smallmatrix}}{\mathop{R-N{{H}_{2}}}}\,\xrightarrow{{}}\] \[\underset{\text{isocyanide}}{\mathop{R-NC}}\,+3{{H}_{2}}O+3KCl\]


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