A) Replication in prokaryotes is conservative while it is semiconservative in eukaryotes
B) Prokaryotes do not require small RNA primer for initiation of replication as in eukaryotes
C) Prokaryotes have single origin of replication and eukaryoteshave multiple origin of replication
D) All of the above
Correct Answer: C
Solution :
Differences between prokaryotic and eukaryotic DNA replication are largely related to contrasts in size and complexity of the DNA and cells of these organisms. The average eukaryotic cell has 25 times more DNA than a prokaryotic cell. In prokaryotic cells, there is only one point of origin, replication Occurs in two opposing directions at the same time and takes place in the cell cytoplasm. Eukaryotic cells on the other hand, have multiple points of origin and use unidirectional replication within the nucleus of the cell. Prokaryotic cells possess one or two types of polymerases, whereas eukaryotes have four or more. Replication also happens at a much faster rate in prokaryotic cells, than in eukaryotes. Some bacteria take only 40 minutes, while animal cells such as humans may take up to 400 hours. In addition, eukaryotes also have a distinct process for replicating the telomeres at the ends of their chromosomes. With their circular chromosomes, prokaryotes have no ends to synthesise. Lastly, the short replication in prokaryotes occurs almost continuously, but eukaryotic cells only undergoes DNA replication during the S-phase of the cell cycle.
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