Manipal Medical Manipal Medical Solved Paper-2010

  • question_answer
    In E. coli, a finished polypeptide has 162 amino acids of which the first amino acid is not a methionine compound. How many nucleotides of DNA are required to code this polypeptide?

    A)  486            

    B)  54

    C)  489            

    D)  492

    Correct Answer: C

    Solution :

     There is an intimate connection between genes and synthesis of polypeptides or enzymes The relationship between the sequence, of amino acids in a polypeptide and nucleotide sequence of DNA or mRNA is called genetic code. To code a polypeptide of 162 amino acids 486   nucleotides   required   but here, methionine is absent. Therefore, 489 nucleotides required and methionine may remove from polypeptide later.


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