NEET Biology NEET PYQ-Enzyme

  • question_answer
    Which one of the following hydrolyses internal phosphodiester bonds in a polynucleotide chain? [AIPMT (S) 2005]

    A) Lipase

    B) Exonuclease

    C)   Endonuclease

    D) Protease

    Correct Answer: B

    Solution :

    [B] DNAase (or deoxyribonuclease) or simply nuclease is an enzyme which breaks down DNA by hydrolysis of the phosphodiester bonds of its sugar-phosphate back bone. Depending on the position of hydrolysing phosphodiester bonds, nucleases are of two types: (i) Endonucleases            (ii) Exonucleases. Endonucleases hydrolyse internal phosphodiester bonds in a polynucleotide chain (i.e., DNA). While exonucleases hydrolyse terminal phosphodiester bonds in a polynucleotide chain (i.e., DNA).


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