A) Aminoglycosides
B) Fluoroquinolones
C) Quinines
D) Penicillins
Correct Answer: D
Solution :
Peptidoglycan, also known as murein is a polymer consisting of sugars and amino acids that forms a mesh-like layer outside the plasma membrane of most bacteria, forming the cell wall. Some antibacterial drugs such as penicillin interfere with the production of peptidoglycan by binding to bacterial enzymes known as penicillin-binding proteins or transpeptidases. For a bacterial cell to reproduce, more than a million peptidoglycan subunits must be attachedto existing subunits. Transpeptides form the bonds between oligopeptide crosslinks in peptidoglycan-penicillin inhibit this binding and kills bacterial cells.
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