12th Class Biology Molecular basis of inheritance

  • question_answer 55)   Who revealed biochemical nature of the transforming principle?


                      Oswald, Avery, Colin MacLeod and Maclyn McCarty revealed biochemical nature of the transforming principle. They reported Griffith's experiment in an in vitro system in order to determine biochemical nature of transforming principle. They reported that. DMA from the neat-killed S-type bacteria caused the transformation of non-virulent R-type bacteria into virulent S-type bacteria. They also discovered that proteases and RNase did not affect transformation while DNase inhibited the process. They concluded that DNA is the hereditary material.

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