If histones were mutated and made rich in
acidic amino acids. They will not be able to serve the purpose of keeping the
DNA coiled around them. This is because DNA is negatively charged molecule and
histones are positively charged because of basic amino acids.
So, they are attracted to each other. If
histones become negatively charged, instead of binding, they will rather repel
DMA. The packaging of DNA in eukaryotes would not happen.
Consequently, the chromatin
fibre would not be formed.
You need to login to perform this action.
You will be redirected in 3 sec