12th Class Biology Principle Of Inheritance And Variation

  • question_answer 67)
      Discuss in detail the contributions of Morgan and Sturvant in the area of genetics.  

    Answer:

                      T H Morgan (1866-1945) was given the Nobel Prize in 1933. His contributions are; (i) Morgan worked on fruit fly Drosophila melanogaster and proposed the chromosomal theory of linkage. (ii) He stated and established that genes are located on the chromosome. (iii) He established the principle of linkage, crossing over, sex-linked inheritance and discovered the relation between gene and chromosome. (iv) He established the technique of chromosome mapping. (v) He observed and worked on mutation. Alfred Henry Sturtevant (1891-1970) student of morgan was given the National Medal of Science in 1967. His contributions are (i) He constructed the first genetic map of a chromosome while working on the Drosophilagenome. (ii) His main contributions to science include his analysis of genetic linkage groups,' which became classical method of chromosome mapping that is still used today. In 1913, he determined that genes were arranged on chromosomes in a linear fashion, like bead son a necklace. He also showed that the gene for any specific trait was in a fixed location(locus). (iii) His work on Drosophila proved that two closely related species showed newly recurring mutations that were allelic and thus probably identical. His work also helped to determine genetic role in sexual selection and development and displayed the importance of chromosomal crossing over in mutations. (iv) One of Sturtevant's principal contributions was his introduction to the concept that the frequency of crossing over between two genes could help to determine their proximity on a linear genetic map. His experiments determined that the frequency of double-crossing over can be used to deduce gene order.


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