| Direction Read the following and answer the questions from given below |
| Many human diseases have genetic component. Some of these conditions are under investigation by researchers or associated with National Human Genome Research Institute (NHGRI). A genetic disorder is a disease caused in whole or in part by change in the DNA sequence away from the normal sequence. Genetic disorders can be caused by a mutations in one gene (monogenic disorder), by mutation in multiple genes (multifactorial inheritance disorder) or by a combination of gene mutations and environmental factors or by damage to chromosomes (changes in the number or structure of entire chromosomes, the structure that carry genes). |
| (i) A hereditary disease which is never passed on from father to son is |
A) autosomal linked disease
B) X-chromosomal linked disease
C) Y-chromosomal linked disease
D) None of the above
Correct Answer: B
Solution :
[b] X-chromosome linked diseases can never be passed on from father to son because, the X-chromosome of the father can only be transferred to daughter and Y-chromosome is only passed on to the son.
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