| Direction Read the following and answer the questions from given below |
| Many human diseases have genetic component. Some of these conditions are under investigation by researchers or associated with National Human Genome Research Institute (NHGRI). A genetic disorder is a disease caused in whole or in part by change in the DNA sequence away from the normal sequence. Genetic disorders can be caused by a mutations in one gene (monogenic disorder), by mutation in multiple genes (multifactorial inheritance disorder) or by a combination of gene mutations and environmental factors or by damage to chromosomes (changes in the number or structure of entire chromosomes, the structure that carry genes). |
| (iv) Failure of segregation of chromatid during cell division cycle, results in the gain or loss of chromosome which is called |
A) aneuploidy
B) hypopolyploidy
C) hyperpolyploidy
D) polyploidy
Correct Answer: A
Solution :
[a] Aneuploidy occurs when the chromatids fail to segregate during cell division, resulting in gain or loss of a chromosome.
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