question_answer

Two different mutations were found in a gene. The gene has been cloned and an antibody is available for the protein product of this gene. Northern and Western analyses were performed on each mutant (1 and 2) and the wild-type gene (Wt,no mutation). The results are shown below. What type of mutation has occurred in the two mutants?

A)  Mutants 1 and 2 both have missense mutations at different positions

B)  Mutant 1 has a missense mutation, while mutant 2 has a silent mutation

C)  Mutant 1 has a missense mutation, while mutant 2 has a nonsense mutation

D)  Mutant 1 has a nonsense mutation, while mutant 2 has a silent mutation