Answer:
Small volume cultures cannot yield appreciable quantities of products. In order to have larger quantities, bioreactors have been developed. Abioreactor provides the optimal conditions substrate, salts, vitamins and oxygen. Bioreactors are used in biotechnology as
(a) In industrial biotechnology for the production of fermented foods, wine, organic acids, etc. (b) It may also be used in environment biotechnology to treat sewage and waste water. (c) Used for the production of recombinant product. (d) Bioreactors are also used in the pharmaceutical industry for the growth of specialised pure cultures of bacteria, fungi, yeast and the production of enzyme, drugs, etc. 
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