A) Primary structures of insulin from different species are identical.
B) Somewhat different amino acid sequences may yield similar 3- dimensional conformations.
C) Three-dimensional conformation has little relation to biological activity.
D) None of the above
Correct Answer: B
Solution :
Protein hormone insulin stimulates receptors on the cell membrane. Most amino acids in the hormone do not participate in the hormone-receptor interaction. The important thing is that the amino acids that do interact are exposed in the proper way. Insulin from different species may have somewhat different primary structure (slightly different amino acids sequence) but its 3-dimensional shape (conformation) is similar in all.
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