A) Okazaki fragments, synthesised \[5'\to 3'\]are linked by DNA ligase
B) An RNA primer is needed on the lagging strand, but not on the leading strand
C) Deoxyribonucleotides are added to the 5' end insteat I the 3' end
D) Helicase synthesises Okazaki fragments, which are then linked together
Correct Answer: A
Solution :
Option [a] is correct as the lagging strand is synthesized discontinuously, the newly synthesized DNAs exist as small fragments (called Okazaki fragments), which are linked together by DNA ligase. Other statements can be corrected as: RNA primer is needed on both the lagging and leading strands. Deoxyribonucleotides are added to the 3'-end. DNA polymerase synthesises Okazaki fragments.
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