| Consider the following about Methicilin-resistant staphylococcus aureus (MRSA) and New Delhi Metallo-beta lactamase (NDM-1): |
| 1. MRSA is a superbug prevalent in developed countries. |
| 2. NDM-1 is another superbug found in developing world. |
| 3. MRSA is causing high percentage of hospital acquired infections. |
| 4. NDM-1 is a community- acquired resistance rather than a hospital acquired resistance. Which of the statements is/are correct? |
A) 1 and 2
B) 3 and 4
C) 1, 2 and 3
D) 1, 2, 3 and 4
Correct Answer: D
Solution :
[d] NDM-1 stands for New Delhi metallo-beta-lactamase, which is an enzyme that destroys beta-lactam antibiotics including the penicillins, cephalosporins, and carbapenems. NDM-1 has been reported most commonly from India and Pakistan but is spreading throughout the world as people travel from country to country. Bacteria from the Enterobacteriaceae family are the most common cause of urinary infections. They can also cause bloodstream infections (sepsis), pneumonia, or wound infections. Symptoms and signs reflect the site of the infection. Most patients will have fever and fatigue. If bacteria enter the bloodstream, patients may go into Symptoms do not differ between bacteria that express NDM-1 and those that do not However, patients who have bacteria producing NDM-1 will not respond to most conventional antibiotics and are at high risk for complications.
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