AIIMS AIIMS Solved Paper-2001

  • question_answer
    The product formed by the reaction of acetamide with bromine in presence of \[NaOH\] is:

    A)  \[C{{H}_{3}}CN\]            

    B)         \[C{{H}_{3}}CHO\]         

    C)         \[C{{H}_{3}}C{{H}_{2}}OH\]   

    D)         \[C{{H}_{3}}N{{H}_{2}}\]

    Correct Answer: D

    Solution :

    This reaction is known as Hofmann- bromamide reaction and is used for conversion of amides to p-amines with one carbon atom less than parent amide. \[\underset{Acetasmide}{\mathop{C{{H}_{3}}CON{{H}_{2}}}}\,+B{{r}_{2}}+4NaOH\to \underset{Methyla\min e}{\mathop{C{{H}_{3}}N{{H}_{2}}}}\,\]                            \[+N{{a}_{2}}C{{O}_{3}}+2KBr+2{{H}_{2}}O\]


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