AIIMS AIIMS Solved Paper-2005

  • question_answer

    Direction for: In each of the following questions a statement of Assertion is given followed by a corresponding statement of Reason just below it. Of the statements mark the correct answer as

    Assertion:           Persons suffering from haemophilia fail to produce blood clotting factor VIII. Reason: Prothrombin producing platelets in such persons are found in very low concentration.

    A) If both Assertion and Reason are true and the Reason is the correct explanation of the Assertion.

    B) If both Assertion and Reason are true but the Reason is not the correct explanation of the Assertion.

    C) If Assertion is true statement but Reason is false.

    D)  If both Assertion and Reason are false statements.

    Correct Answer: C

    Solution :

    Haemophilia is a hereditary (X-linked recessive) disease in which blood fails to clot due to absence of factor-VIII. Insertion of LINE transposable element into the factor VIII gene is responsible for this classic haemophilia. This disease is also called haemophilia-A. Haemophilia-B or Christmas disease occurs due to factor IX (plasma thromboplastin comporent) deficiency. Prothrombin producing platelets in such person are not found in very low concentration.


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