A) \[N{{a}^{+}}\] ions help in stopping nerve impulses and hence sensation of pain
B) \[N{{a}^{+}}\] ions help in the retention of water in the body tissues
C) NaCl is an important component of energy supply
D) NaCI furnishes most of the fuel required for cellular activity
Correct Answer: B
Solution :
Severe diarrhoea, vomitting, watery stools are the chief symptoms of cholera. All these lead to dehydration. Actually, cholera toxin secreted by Vibrio cholerae causes, through a series of metabolic reactions, the continuous activation of adenylate cyclase of intestinal epithelial cells. The resultant high concentration of cAMP triggers continual secretion of \[C{{l}^{-}},\,HCO_{3}^{-}\] and water into the lumen of the intestine. Administration of saline not only supports the sodium-potassium pump through which water in cell is restored, but glucose is also symported along with sodium.
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